
Widely found in essential oils of natural plants such as clove, basil and black pepper, Caryophyllene Oxide is an oxidized derivative of β-Caryophyllene. It appears as white crystalline powder with a melting point of 62-63℃ and purity up to over 95%. Boasting excellent high-temperature stability, its fragrance hardly volatilizes at a boiling point of 279-301℃, making it perfectly adaptable to various processing scenarios. It features a unique fresh woody aroma blended with mild spicy and sweet notes, with fresh top note, mellow body note and long-lasting sweet aftertaste, serving as an indispensable flavor skeleton in natural perfumery.
In the food industry, Caryophyllene Oxide acts not only as a high-quality spice ingredient but also an ideal natural preservative. Compliant with China’s GB 2760 standard for food additives, it can be used to prepare various food flavors and endow products with unique taste. Meanwhile, it delivers remarkable inhibitory effect on pathogenic bacteria such as Klebsiella pneumoniae, with an inhibition rate reaching 78.3% at a concentration of 0.8 mg/mL, effectively extending the shelf life of food. It has been widely applied in baked goods, beverages, condiments and more. An addition ratio of merely 0.05%-0.3% in biscuits, milk tea powder and other products can realize dual improvement of flavor and fresh-keeping performance.
Caryophyllene Oxide also gains great attention for its functional value in daily chemical and pharmaceutical sectors. As a novel transdermal absorption enhancer, it disrupts the ordered arrangement of corneal lipids and keratin, significantly improving the permeability of the skin barrier. Its penetration-promoting effect on polar macromolecules outperforms traditional terpenoid enhancers, with low irritation and high safety, making it a preferred ingredient for cosmetics and external pharmaceutical preparations. Pharmacological studies show that its combined use with paracetamol can boost analgesic effect by 32% and reduce the incidence of gastric mucosal damage. Its derivatives also have potential activities including anti-parasitic and cholinesterase inhibition, opening up new directions for pharmaceutical research and development.

With breakthroughs in green production technology, domestic enterprises have realized high-purity extraction and stable mass production of Caryophyllene Oxide. Adopting eco-friendly extraction processes for precise extraction from natural plant raw materials, the conversion rate and selectivity have reached advanced industry levels. This plant-derived ingredient is easily biodegradable with no environmental pollution, fully meeting the demand for sustainable development. It can replace part of chemical preservatives and insect repellents, catering to the consumption trend of natural ingredients.
Industry experts point out that the cross-field application of Caryophyllene Oxide is embracing a golden development period, and the global market scale is expected to exceed 500 million RMB by 2030. With core strengths of natural traceability, diversified functions and environmental friendliness, it will drive the food, daily chemical and pharmaceutical industries toward a healthier and more sustainable future, bringing superior product experience to consumers.
Post time:2026-04-29