Product Specifications
Chemical Name: N-(4-Methoxyphenyl)-p-menthane-3-carboxamide, (1R,2S,5R)-2-isopropyl-N-(4-methoxyphenyl)-5-methylcyclohexanecarboxamide
CAS Number: 68489-09-8
FEMA Number: 4681
Molecular Formula: C₁₈H₂₇NO₂
Molecular Weight: 289.41 g/mol
Appearance: White to off-white crystalline powder
Purity: ≥ 99%
Melting Point: 177 – 183°C
Boiling Point: ~447°C
Solubility: Insoluble in water; soluble in alcohol and oils
Shelf Life: 36 months when stored properly
Storage: Keep in cool, dry place away from direct sunlight and heat sources; ensure container is tightly sealed after each use
Product Overview
WS-12 Cooling Agent (N-(4-Methoxyphenyl)-p-menthane-3-carboxamide) is a premium synthetic food-grade cooling agent that delivers a powerful initial cooling impact with remarkably long-lasting freshness. As a menthol derivative, WS-12 exhibits significantly higher potency than menthol and provides a stronger initial cooling effect along with more sustained duration compared to WS-3, WS-5, and WS-23 . Unlike menthol, WS-12 produces minimal odor and no irritating pungency, offering a clean, refreshing cooling sensation that enhances products without altering their intended flavor profiles .
Cooling Profile
The cooling agent offers a distinctive sensory experience with the following characteristics:
Superior initial cooling impact: Provides strong, immediate cooling that activates the palate instantly, with higher potency than menthol or other WS-series agents
Extended duration: Cooling sensation persists for 10–30 minutes, significantly longer than menthol
Targeted cooling areas: Focuses primarily on the throat area, producing a lasting fresh finish
Clean, non-pungent profile: Minimal odor with mild menthol-like notes; no bitterness, burning, or irritating effects
Heat stability: Maintains cooling effectiveness at temperatures up to 200°C, suitable for baking and heat-processed applications
Key Features
High cooling potency: Low dosage required—typically 15–100 mg/kg for strong effect
Excellent thermal stability: Retains cooling properties under high-temperature processing (up to 200°C)
Synergistic compatibility: Works well with other cooling agents and flavors for enhanced profiles; used with WS-3, WS-5, WS-23 in combinations
Non-irritating: Gentle on skin and mucous membranes, suitable for sensitive applications
Regulatory compliant: Listed under FEMA 4681 and JECFA 2079; approved as a food additive